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California State University, Long Beach
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Investigator Assurance of Compliance Form

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Investigator Assurance of Compliance with CSU Long Beach Guiding Principles and Policies Governing the Care and Use of Animals

In meeting its ethical and legal responsibilities for the use of animals in research and education, California State University Long Beach must assure that all such projects or activities are properly carried out, and that animal users assume their responsibilities. The following guiding principles are drawn primarily from the U.S. Department of Health and Human Services, the U.S. Department of Agriculture, and the American Veterinary Medical Association.

  1. The policies of CSU Long Beach and regulatory agencies must be followed by the Principal Investigator, who is responsible for insuring that his/her employees do the same. Protocols involving animal use will be reviewed by the CSU Long Beach Institutional Animal Care and Use Committee (IACUC). This Committee's approval must be obtained before any activity is initiated. Any request for modifications to animal use protocols must be communicated in writing to the IACUC and approved by the IACUC prior to implementation.
  2. Prior to submitting a protocol to the IACUC, the Principal Investigator will have consulted appropriate sources (e.g., biological abstracts, Index Medicus, the Current Research Information Service (CRIS), and the Animal Welfare Information Center operated by the National Agricultural Library) to ensure that the proposed work will not unnecessarily duplicate previous experiments and that the proposed work cannot be carried out in non-animal models.
  3. The project or activity will be designed and based on knowledge of the disease or problem under study such that the significance of anticipated results will justify its performance. Through refinement of experimental design and application of sound statistical methods, the appropriate number of animals to achieve valid results will be used.
  4. The approved project or activity will be performed by, or under the immediate supervision of, a CSU Long Beach Primary Investigator qualified in the scientific area under study, in consultation with the Attending Veterinarian, and is subject at all times to an on-site review by the IACUC or its designates.
  5. Principal Investigator is responsible to assure that personnel conducting procedures on the species being maintained or studied will be appropriately qualified and trained in those procedures. All personnel will receive a copy of the protocol.
  6. Procurement of animals for approved projects will be contingent upon available housing. All commercially obtained and wild-caught animals must be procured in compliance with approved protocols in advance with the CSU Long Beach Research Facilities Coordinator (x54459). They will be maintained with due consideration for comfort, feeding, watering, sanitation, and disease control under the direction of the Research Facilities staff and Attending Veterinarian. Only authorized personnel directly involved with animal research will be permitted in the Vivarium.
  7. Procedures with animals that may cause more than momentary or slight pain or distress should be performed with appropriate sedation, analgesia, or anesthesia. Surgical or other painful procedures should not be performed on unanesthetized animals paralyzed by chemical agents. Animals that would otherwise suffer severe or chronic pain or distress that cannot be relieved should be painlessly killed at the end of the procedure or, if appropriate, during the procedure.
  8. All survival surgery, including rodent survival surgery, will be done in compliance with CSULB policy and approved protocols.
  9. When it is necessary to euthanitize an animal, the approved method of euthanasia will be employed. No animal will be discarded until its death is certain. Dead animals will be disposed of in accordance with the approved protocol.

I have read and understood these Guiding Principles and policies governing the use of animals in research, teaching, and observation; and I agree to accept responsibility that all animal use in the proposed project or activity will be in accordance with Federal and other relevant policies and regulations.

Name of Principal Investigator (Print or Type):
Signature of Principal Investigator and Date:

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