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Biological Sciences

College of Natural Sciences and Mathematics

CSULB students study

Microbiology - MICR Courses

Students pursuing a major and/or a minor in this department may receive unit credit for courses marked with the symbol ‘##’ as a general elective but may not apply the units toward the specific or elective requirements for any degree or option in this department. Majors in this Department may, however, take, for general education purposes, interdisciplinary courses offered by this department. All other courses in this department are open to majors and minors but by letter grade only.

LOWER DIVISION

101. ## Introduction to Human Disease (3) F, S

Prerequisite/Corequisite: Course that fulfills the A.1 GE requirement.
Introduction to the study of human disease including moral/ethical and economic issues.
(Lecture 3 hrs.)

200. General Microbiology for Health

Professionals (4) F, S
Prerequisites: CHEM 111A or 140 with a grade of “C” or better and completion of GE Foundation requirements.
Microbiology for those planning careers in nursing, health care and education, and foods and nutrition. Introduction to microorganisms, including structure, function, metabolism, growth, genetics, diversity, and applied aspects. Special emphasis on human health.
Not open for credit to majors in the biological sciences. (Lecture 2 hrs., laboratory 6 hrs.) Course fee may be required.

211. General Microbiology (5) F,S

Prerequisites: BIOL 111, 111L, 212, 212L; CHEM 111B, all with a grade of "C" or better.
Introduction to biology of microorganisms, including structure, function, metabolism, growth, genetics, diversity, host-parasite relationships, and applied aspects.
Letter grade only (A-F). (Lecture 3 hrs., laboratory 6 hrs.) Course fee may be required.

UPPER DIVISION

300I. ## Human Immunology: In Self-Defense (3) F

Prerequisites: Completion of GE Foundation requirements, one or more Explorations courses, and upper-division standing; one laboratory course in a life science. Introductory psychology and a laboratory course in a physical science recommended.
Mechanisms and cells responsible for protecting human body from disease. Normal functions of immune system, diseases involving immune system, and psychological, endocrine and age factors affecting immune system included. Impact of immunology or organ transplantation, immunotherapy, and biotechnology discussed.
Not applicable for credit toward the major in Microbiology. (Lecture 3 hrs.)

320. Bacterial Pathogenesis (3) F,S

Prerequisite: MICR 211 with a grade of “C” or better.
Nature of host-pathogen interactions in health and disease. Emphasis upon pathogenic bacteria of humans and animals; topics include bacterial ultrastructure, epidemiology, and mechanisms of pathogenesis, host defense mechanisms, and antibiotic therapy.
Letter grade only (A-F). (Lecture 3 hrs.) Course fee may be required.

320L. Bacterial Pathogenesis Laboratory (2) F,S

Prerequisite or corequisite: MICR 320 with a grade of “C” or better.
Experiments using modern and classical techniques for the isolation, identification, and characterization of pathogenic bacteria. Molecular mechanisms of bacterial virulence are emphasized. Techniques used include PCR, SDS-PAGE, serotyping, and immunofluorescence microscopy.
Letter grade only (A-F). (Laboratory 6 hrs.)

322. Mycology/Parasitology (5) F,S

Prerequisites: BIOL 111, 111L, 212, 212L; MICR 320, all with a grade of "C" or better.
Second of a two-semester sequence (MICR 320/322) in medical microbiology for majors. Survey of parasitic protozoa, helminthes, and fungi of humans; emphasis on identification of fresh and preserved specimens, pathogenesis, host-parasite interactions, epidemiology, prevention, and control.
Letter grade only (A-F). (Lecture 3 hrs., laboratory 6 hrs.) Course fee may be required.

325. Emerging Infectious Diseases (3)

Prerequisites: MICR 211 with a grade of “C” or better and consent of instructor.
Explores changes in technology, infectious disease organisms and other factors contributing to emerging and re-emerging infectious diseases, including immunodeficiency, antibiotic and insecticide abuses, climate change, travel and commerce, human demographic and behavioral changes, land use, and breakdown of public health.
Letter grade only (A-F). (Lecture 3 hrs.)

355. Microbial Ecology (3) S

Prerequisites: MICR 211 or BIOL 111, 111L, 212, 212L, 213, 213L, all with a grade of "C" or better.
Explores relationships of microorganisms to their environment. Emphasis placed on ecological basis for diversity of prokaryotic forms, metabolic functions and community interactions.
Not open for credit to students with credit in BIOL 355. Letter grade only (A-F). Same course as BIOL 355. (Lecture 3 hrs.)

355L. Microbial Ecology Laboratory (1) S

Prerequisite: MICR 355 or BIOL 355 with a grade of “C” or better.
Provides an understanding of microbes in the environment. Sample and analyze microbes from field trips to different habitats. Analytical techniques learned include enrichment culture methods and modern molecular biology methods to study the diversity and community dynamics of microbes.
Not open for credit to students with credit in BIOL 355L. Letter grade only (A-F). Course fee may be required. Same course as BIOL 355L. (Laboratory 3 hrs.)

371. Microbial Genetics (3) F

Prerequisite: MICR 211 with a grade of “C” or better.
Genetic analysis of biological processes in microbes. Includes gene structure, regulation, and function; isolation/analysis of mutations in haploid/diploid organisms; gene function from mutants; genetic exchange; regulation of host-pathogen interactions; bacteriophages; cloned genes; and genomics.
Letter grade only (A-F). (Lecture 3 hrs.)

372. Methods in Microbial Genetics (2) F

Prerequisite: MICR 211 with a grade of “C” or better. Recommended: MICR 371.
Laboratory study of microbial genetics, using classical (non-molecular) and contemporary (molecular) approaches. Includes genetic engineering techniques; microbial genomics.
Not open for credit to students with credit in MICR 451. Letter grade only (A-F). (Laboratory 6 hrs.) Course fee may be required.

415./515. Marine Microbiology (3) F, odd years

Prerequisite: MICR 355 or BIOL 355 or BIOL 353 with a grade of “C” or better. (Undergraduates enroll in MICR 415; graduates enroll in MICR 515.)
Designed to familiarize microbiology and marine biology students with the role of microorganisms in the marine environment. Topics will include ecology, physiology, biogeochemistry, and diversity of marine microbes. Laboratory/field component will emphasize examination and cultivation of local marine microbes.
Not open for credit to students with credit in BIOL 415. Letter grade only (A-F). Course fee may be required. Same course as BIOL 415. (Lecture 2 hrs., laboratory and field 3 hrs., weekend field trip may be required.)

416./516. Virology (3) F,S

Prerequisite: MICR 320 or BIOL 340 with a grade of "C" or better. (Undergraduates enroll in MICR 416; graduates enroll in MICR 516.)
Virology at molecular level including viral replication and molecular basis for viral pathogenesis; survey of human, animal, and plant viral diseases. Current trends for prevention and treatment of viral diseases.
Letter grade only (A-F). Same course as BIOL 516. Not open for credit to students with credit in BIOL 516. (Lecture 3 hrs.)

423./523. Hematology (4) F

Prerequisite: BIOL 340 with a grade of “C” or better. (Undergraduates enroll in MICR 423; graduates enroll in MICR 523.)
Study of blood and coagulation system. Normal cell structure and function and physiological and morphological changes in inflammation, leukemias, and anemias discussed. Clinical, diagnostic, and research techniques for observing blood and pathologic case-studies included.
Useful for student interested in medical professions. Required for clinical laboratory science (medical technology) internship. Letter grade only (A-F). (Lecture 3 hrs., laboratory 3 hrs.) Course fee may be required.

429./529. Epidemiology of Infectious Diseases (3)

Prerequisites: BIOL 260; MICR 320, 322; all of a grade of "C" or better. (Undergraduates enroll in MICR 429; graduates enroll in MICR 529.)
Principles of epidemiology and application to health; fundamentals of biomedical statistics; basic factors in classic epidemiological studies and prevention and control of infectious diseases.
Letter grade only (A-F). (Lecture 3 hrs.)

430. Immunology (3) F,S

Prerequisite: BIOL 340 with a grade of “C” or better.
Study of cellular and molecular components of immune system, including how immune system recognizes pathogens, how it functions in various types of immune responses, mechanisms of vaccines, immunodeficiencies, transplantation, allergy, and autoimmunity.
Not open for credit to students with credit in BIOL 430. Letter grade only (A-F). Same course as BIOL 430. (Lecture 3 hrs.)

430L. Immunology Laboratory (2)

Prerequisite: BIOL 340 with a grade of “C” or better. Prerequisite/Corequisite: MICR 430.
Modern and classical techniques in cellular and molecular immunology. Experimental techniques have broader applications to other fields and include mammalian cell culture, antibody purification, SDS-PAGE, western blots, and assays of apoptosis, cell proliferation, cellular activation, and antibody-antigen interactions.
Letter grade only (A-F). (Laboratory 6 hrs.) Course fee may be required.

471./571. Bacterial Physiology (3) S

Prerequisites: MICR 320, CHEM 441A; both with a grade of "C" or better. (Undergraduates enroll in MICR 471; graduates enroll in MICR 571.)
Cellular physiology at molecular level as related to bacterial growth, reproduction, nutrition, metabolism, and ecology.
Letter grade only (A-F). (Lecture 3 hrs.)

473. Food and Industrial Microbiology (3) F

Prerequisites: MICR 200 or 211; CHEM 441A or 448; both with a grade of “C” or better.
Role of microorganisms in food and other industrial processes; emphasis on bacteria, yeasts and molds.
Letter grade only (A-F). (Lecture 2 hrs., laboratory 3 hrs.) Course fee may be required.

477./577. Biotechnology: Applications of Molecular Techniques and Bioinformatics (4) F

Prerequisite: BIOL 340 or 370 or CHEM 441A,B; all with a grade of "C" or better. (Undergraduates enroll in MICR 477; graduates enroll in MICR 577.)
Theory and techniques for isolating, amplifying, and analyzing genes, genomes, transcripts, and proteins. Data-mining, the use of computers in experimental design and/or functional analysis, use of microarrays, and future of nanotechnology.
Letter grade only (A-F). (Lecture 3 hrs., activity 2 hrs.)

490./590. Special Topics in Microbiology (1-3)

Prerequisites: MICR 211 with grade of “C” or better, and consent of instructor. (Undergraduates enroll in MICR 490; graduates enroll in MICR 590.)
Topics from selected areas of microbiology. Course content will vary from section to section. Topics announced in the Schedule of Classes.
May be repeated to a maximum of 6 units with different topics. Letter grade only (A-F). (Lecture 1-3 hrs.)

495. Instruction in Laboratory Teaching (1-2) F,S

Prerequisites: Consent of lecture instructor, a “B” or better in the course in which the student elects to do MICR 495 (another course with laboratory may be substituted with consent of instructor), and an overall GPA of at least 2.75.
Individual instruction in organization and techniques of teaching a microbiology laboratory.
Not open for credit to students with credit in BIOL 495. May be repeated for letter grade and degree credit to a maximum of two units for any single degree or option. Any units beyond the two taken for a letter grade in BIOL 495 or MICR 495 or any combination of the two will be taken credit/no credit. Same course as BIOL 495. (Conference 1 hr., laboratory 3 hrs. per unit.)

496. Undergraduate Directed Research (1-3) F,S

Prerequisites: Consent of instructor and consent of appropriate undergraduate advisor.
Research in a specific topic in biological sciences approved and directed by a faculty member in Department of Biological Sciences.
Not open for credit to student with credit in BIOL 496. May be repeated for a letter grade and degree credit to a maximum of three units for any single degree or option. Any units beyond the three taken for a letter grade in BIOL 496 or MICR 496, or any combination of the two, will be taken credit/no credit. Same course as BIOL 496. Not available to graduate students. (Conference 1 hr., laboratory 3 hrs. per unit.)

GRADUATE LEVEL

515./415. Marine Microbiology (3) F, odd years

Prerequisite: MICR 355 or BIOL 355 or BIOL 353 with a grade of “C” or better. (Undergraduates enroll in MICR 415; graduates enroll in MICR 515.)
Designed to familiarize microbiology and marine biology students with the role of microorganisms in the marine environment. Topics will include ecology, physiology, biogeochemistry, and diversity of marine microbes. Laboratory/field component will emphasize examination and cultivation of local marine microbes.
Not open for credit to student with credit in BIOL 415. Letter grade only (A-F). Course fee may be required. Same course as BIOL 515. (Lecture 2 hrs., laboratory and field 3 hrs., weekend field trip may be required.)

516./416. Virology (3) F,S

Prerequisite: MICR 320 or BIOL 340 with a grade of "C" or better. (Undergraduates enroll in MICR 416; graduates enroll in MICR 516.)
Virology at molecular level including viral replication and molecular basis for viral pathogenesis; survey of human, animal, and plant viral diseases. Current trends for prevention and treatment of viral diseases.
Letter grade only (A-F). (Lecture 3 hrs.)

523./423. Hematology (4) F

Prerequisite: BIOL 340 with a grade of “C” or better. (Undergraduates enroll in MICR 423; graduates enroll in MICR 523.)
Study of blood and coagulation system. Normal cell structure and function and physiological and morphological changes in inflammation, leukemias, and anemias discussed. Clinical, diagnostic, and research techniques for observing blood and pathologic case-studies included.
Useful for student interested in medical professions. Required for clinical laboratory science (medical technology) internship. Letter grade only (A-F). (Lecture 3 hrs., laboratory 3 hrs.)

529./429. Epidemiology of Infectious Diseases (3)

Prerequisites: BIOL 260; MICR 320, 322; all of a grade of "C" or better. (Undergraduates enroll in MICR 429; graduates enroll in MICR 529.)
Principles of epidemiology and application to health; fundamentals of biomedical statistics; basic factors in classic epidemiological studies and prevention and control of infectious diseases.
Letter grade only (A-F). (Lecture 3 hrs.)

571./471. Bacterial Physiology (3)

Prerequisites: MICR 320, CHEM 441A; both with a grade of "C" or better. (Undergraduates enroll in MICR 471; graduates enroll in MICR 571.)
Cellular physiology at molecular level as related to bacterial growth, reproduction, nutrition, metabolism, and ecology.
Letter grade only (A-F). (Lecture 3 hrs.)

577./477. Biotechnology: Applications of Molecular Techniques and Bioinformatics (4) F

Prerequisite: BIOL 340 or 370 or CHEM 441A,B; all with a grade of "C" or better. (Undergraduates enroll in MICR 477; graduates enroll in MICR 577.)
Theory and techniques for isolating, amplifying, and analyzing genes, genomes, transcripts, and proteins. Data-mining, the use of computers in experimental design and/or functional analysis, use of microarrays, and future of nanotechnology.
Letter grade only (A-F). (Lecture 3 hrs., activity 2 hrs.)

590./490. Special Topics in Microbiology (1-3)

Prerequisites: MICR 211 with grade of “C” or better, and consent of instructor. (Undergraduates enroll in MICR 490; graduates enroll in MICR 590.)
Topics from selected areas of microbiology. Course content will vary from section to section. Topics announced in the Schedule of Classes.
May be repeated to a maximum of 6 units with different topics. Letter grade only (A-F). (Lecture 1-3 hrs.)

661. Seminar in Microbiology (2)

Prerequisite: Consent of instructor.
Critical evaluation of literature in this field, including oral and/or written presentation of critiques.
May be repeated to a maximum of 4 units with different topics. Letter grade only (A-F) (Seminar 2 hours)

697. Directed Research (1-3) F,S

Prerequisite: Consent of instructor.
Research on specific topic approved and directed by faculty member in the biological sciences. Written report required.
May be repeated for a letter grade and degree credit to a maximum of three units. Any units beyond the three taken for a letter grade in BIOL 697 or MICR 697 or any combination of the two must be taken credit/no credit.

698. Thesis (1-6) F,S

Prerequisites: Advancement to Candidacy for the Master of Science in Microbiology, consent of the chair of the thesis committee and the departmental graduate advisor.
Planning, preparation, writing, defense, oral presentation, and completion of a research thesis in the biological sciences.
Letter grade only (A-F).