Wednesday, December 17, 2014
(Refreshments served at 10:45am in HSCI-224)
Fig: The essential role of signal processing in magnetic resonance: Upper left: magnetic resonance imaging (MRI); Lower right: magnetic resonance spectroscopy (MRS)
Magnetic resonance spectroscopy (MRS) can provide information about key metabolites, but conventional applications are hampered by data analysis via the fast Fourier transform (FFT). Most MRS studies for cancer detection rely upon estimations of a handful or single composite metabolite, yielding only incrementally improved diagnostic accuracy. In vitro studies reveal richer metabolic information for identifying cancer, particularly in closely-overlapping components, e.g. phosphocholine, a marker of malignant transformation. The FFT cannot assess these congested spectral components. This can be done by the fast Padé transform (FPT), a high-resolution, quantification-equipped method. The FPT accurately extracts the concentrations of all the metabolites, including phosphocholine. These capabilities strongly suggest that by applying the FPT to time signals encoded in vivo from various cancers, MRS will fulfill its potential to become a clinically-reliable, cost-effective method for early cancer detection.
See the colloquium schedule and its archive of previous talks
Colloquia are scheduled to start Mondays at 11:15am sharp in Peterson Hall 2, Room 110 (PH2-110, map). Refreshments are served from 10:45am to 11:05am in Room HSCI-224 (next to the department office) and everyone is invited to mingle with faculty and students!
We acknowledge with gratitude donations and support from the following present sponsors:
We also acknowledge with gratitude our past donors: The Forty-Niner Shops, Inc., The Northrop Grumman Foundation, Sandra Dana, Anonymous.
If you wish to support the Colloquium, please contact the colloquium coordinator or the department chair. Thank you!
|Date||Title||Speaker and Affiliation|
|June 2||Development of Micro-Devices for Intra-Cellular Recordings in Awake Active Brains||M. Barbic, HHMI|
|September 8||Physics Deparment Meet & Mix||Faculty and
|September 15||Density Functional Theory: A great physics success story||Kieron Burke, UC Irvine|
|September 22||BME/Medical Physics; Assisted management of cardiopulmonary diseases||Christopher Druzgalski, CSULB|
|September 29||Radiationless Decay Studied by Time- Dependent Density Functional Theory||Enrico Tapavicza, CSULB|
|October 6||Electronic correlations in multi-orbital systems and iron based superconductors||Elena Bascones: ICMM, CSIC|
|October 13||Searches for Particle Dark Matter||Tim Tait, UCI|
|October 20||Theoretical Approaches towards HIV Vaccine Designs and Prevention Efforts||Ha Youn Lee, USC|
|October 27||Simulation and spectroscopy of many-body systems with cold atoms and molecules||Wes Campbell, UCLA|
|November 3||Probing the Interior of Neutron Stars through Non-radial Oscillations||Prashanth Jaikumar, CSULB|
|November 10||Spin Dynamics Applied to Iron Phthalocyanine||Thomas Gredig, CSULB|
|November 17||Atomic, Molecular and Optical Physics: A Tool to Reveal and Harness Nature’s Most Cherished Secrets||Wendell T. Hill, III, UMD|
|November 24||Understanding Stellar Neutrinos||Michael Smy, UCI|
|December 1||Self-Organized Pattern Formation in Thin Liquid Films||Michael Bestehorn, BTU (Germany)|
|December 5||Student Presentations I||CSULB Students|
|December 8||Student Presentations II||CSULB Students|